A simple blood test can reveal hidden inflammation that predicts heart attacks years before symptoms appear. Learn how this silent marker exposes cardiovascular risk early and how you can protect your heart in time.

Heart Attacks Rarely Begin in the Heart
Most heart attacks do not begin with blocked arteries — they begin with silent arterial inflammation years earlier.
During this silent phase, inflammatory immune cells infiltrate artery walls, weaken plaque stability, and damage vascular lining. This process often continues unnoticed while cholesterol and blood pressure remain within “normal” limits.
By the time chest pain or shortness of breath occurs, arterial damage is often advanced.
Modern preventive cardiology now uses specialized blood markers to detect this inflammatory phase early — allowing heart attacks to be prevented before they develop.

The Inflammation Marker That Changed Cardiology: GlycA
GlycA is one of the strongest predictors of cardiovascular events currently available. Unlike CRP, it reflects chronic inflammatory burden — not short-term infection.
Elevated GlycA predicts:
• Heart attacks
• Strokes
• Insulin resistance
• Autoimmune disease
• Early mortality
Years before symptoms appear.
Why Cholesterol Alone Is Not Enough
Many heart attacks occur in people with “normal cholesterol.” Cholesterol measures fat transport — not vascular inflammation.
Arterial inflammation causes plaque rupture, clot formation, and vessel blockage — the true cause of heart attacks.
GlycA reveals this risk early.
Additional Heart Protection Biomarkers
| Marker | What It Detects |
|---|---|
| Lp-PLA2 | Plaque inflammation |
| Homocysteine | Endothelial injury |
| suPAR | Vascular stress |
| Oxidized LDL | Arterial damage |
Who Should Get Inflammation Screening?
• Adults over 30
• People with family history of heart disease
• Smokers
• Diabetics or pre-diabetics
• Individuals with fatigue or weight gain
Early Detection Saves Lives
When inflammation is detected early:
• Arterial lining can heal
• Plaque stabilizes
• Blood sugar normalizes
• Stroke risk falls
• Medication need decreases
Silent Inflammation Predictors (Beyond CRP)
CRP is saturated.
But these are not:
| Hidden Marker | Detects |
|---|---|
| GlycA | Chronic low-grade inflammation |
| suPAR | Early mortality risk |
| Lp-PLA2 | Arterial inflammation |
| IL-6 (clinical use) | Pre-heart attack signaling |
Hidden Blood Markers That Detect Disease Years Before Diagnosis
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Conclusion
Heart attacks begin years before symptoms appear — but they can now be predicted and prevented.
GlycA and related biomarkers give you that early warning window.
Medical Disclaimer
Educational only. Consult your physician before testing.
Dr. Mohammed Abdul Azeem Siddiqui, MBBS, M.Tech (Biomedical Engineering – VIT, Vellore)
Registered Medical Practitioner – Reg. No. 39739
Physician • Clinical Engineer • Preventive Diagnostics Specialist
Dr. Mohammed Abdul Azeem Siddiqui is a physician–engineer with over 30 years of dedicated clinical and biomedical engineering experience, committed to transforming modern healthcare from late-stage disease treatment to early detection, preventive intelligence, and affordable medical care.
He holds an MBBS degree in Medicine and an M.Tech in Biomedical Engineering from VIT University, Vellore, equipping him with rare dual expertise in clinical medicine, laboratory diagnostics, and medical device engineering. This allows him to translate complex laboratory data into precise, actionable preventive strategies.
Clinical Mission
Dr. Siddiqui’s professional mission centers on three core pillars:
Early Disease Detection
Identifying hidden biomarker abnormalities that signal chronic disease years before symptoms appear — reducing complications, hospitalizations, and long-term disability.
Preventive Healthcare
Guiding individuals and families toward longer, healthier lives through structured screenings, lifestyle intervention frameworks, and predictive diagnostic interpretation.
Affordable Evidence-Based Treatment
Delivering cost-effective, scientifically validated care accessible to people from all socioeconomic backgrounds.
Clinical & Technical Expertise
Across three decades of continuous practice, Dr. Siddiqui has worked extensively with:
Advanced laboratory analyzers and automation platforms
• Cardiac, metabolic, renal, hepatic, endocrine, and inflammatory biomarker systems
• Preventive screening and early organ damage detection frameworks
• Clinical escalation pathways and diagnostic decision-support models
• Medical device validation, calibration, compliance, and patient safety standards
He is recognized for identifying subclinical biomarker shifts that predict cardiovascular disease, diabetes, fatty liver, kidney disease, autoimmune inflammation, neurodegeneration, and accelerated biological aging long before conventional diagnosis.
Role at IntelliNewz
At IntelliNewz, Dr. Siddiqui serves as Founder, Chief Medical Editor, and Lead Clinical Validator. Every article published is:
Evidence-based
• Clinically verified
• Technology-grounded
• Free from commercial bias
• Designed for real-world patient and physician decision-making
Through his writing, Dr. Siddiqui shares practical health intelligence, early warning signs, and preventive strategies that readers can trust — grounded in decades of frontline medical practice.
Contact:
powerofprevention@outlook.com
📌 Disclaimer: The content on IntelliNewz is intended for educational purposes only and does not replace personalized medical consultation. For individual health concerns, please consult your physician.



